Pinning and propagation in spatially discrete bistable systems

Depto. de Análisis Matemático y Matemática AplicadaFac. de Ciencias MatemáticasFALSEunpu

Propagación de impulsos nerviosos

Depto. de Análisis Matemático y Matemática AplicadaFac. de Ciencias MatemáticasFALSEunpu

European consumer segments with a high potential for accepting new innovative fish products based on their food-related lifestyle

Consumer lifestyles influence consumer behaviour towards food product choices and provide important insights about the existence of consumer segments that vary in their response to new food products. With the aim to contribute to a more market-oriented enhancement of the European aquaculture industry competitiveness, the objective of this study was to identify and profile food-related lifestyle segments of consumers that vary in terms of their willingness to buy new aquaculture fish products. Data were collected through a survey among respondents in three large European fish markets (Spain, France and Germany, N = 1500 in total). Certain core dimensions of the food-related lifestyle construct were used as segmentation bases. We identified five consumer segments across two country groups. The segments differed mainly in terms of their psychographic profile and their intention to buy new aquaculture fish products. Our results contribute to identifying the most promising European consumer segments in terms of buying intention that can be targeted when promoting new aquaculture fish products. The findings have important strategic marketing implications for the food industry and aquaculture, while highlighting the important role food-related lifestyles can play in European segmentation for new food product development.info:eu-repo/semantics/publishedVersio

Sobre la fundamentación moral de la desobediencia al Derecho

La cuestión de la obediencia al Derecho es uno de los fenómenos más controvertidos para la Filosofía del Derecho. En el presente trabajo, he analizado algunas de las principales corrientes filosóficas que a lo largo de la Historia de la Filosofía han tratado de justificar la desobediencia al Derecho, introduciendo también mi postura personal en el tema: no es sino en la moralidad donde reside el verdadero fundamento de la obediencia al Derecho. Sin embargo, siendo los imperativos de la conciencia los únicos preceptivos de forma absoluta, estos exigirán no obedecerlo cuando el mismo sea considerado por la moral como injusto

Ajustes en el procedimiento judicial para personas con discapacidad intelectual: La figura del facilitador

Desde la celebración de la Convención de los Derechos de las Personas con Discapacidad Intelectual se ha debatido sobre los ajustes necesarios en el procedimiento judicial debido a las barreras que afrontan las personas con discapacidad intelectual en el mismo. Con la colaboración de Plena Inclusión Aragón, buscamos justificar la existencia de una figura de apoyo llamada facilitador, para que se cumplan los derechos que se les garantiza en dicha Convención y que se permita un acceso a la justicia en igualdad de condiciones para estas personas.<br /

Ajustes en el procedimiento judicial para personas con discapacidad intelectual. La figura del facilitador.

Desde la celebración de la Convención de los Derechos de las Personas con Discapacidad Intelectual se ha debatido sobre los ajustes necesarios en el procedimiento judicial debido a las barreras que afrontan las personas con discapacidad intelectual en el mismo. Con la colaboración de Plena Inclusión Aragón, buscamos justificar la existencia de una figura de apoyo llamada facilitador, para que se cumplan los derechos que se les garantiza en dicha Convención y que se permita un acceso a la justicia en igualdad de condiciones para estas personas.<br /

The Use of Mucoadhesive Polymers to Enhance the Hypotensive Effect of a Melatonin Analogue, 5-MCA-NAT, in Rabbit Eyes

Purpose.: 5-Methoxy-carbonylamino-N-acetyltryptamine (5-MCA-NAT, a melatonin receptor agonist) produces a clear intraocular pressure (IOP) reduction in New Zealand White rabbits and glaucomatous monkeys. The goal of this study was to evaluate whether the hypotensive effect of 5-MCA-NAT was enhanced by the presence of cellulose derivatives, some of them with bioadhesive properties, as well as to determine whether these formulations were well tolerated by the ocular surface. Methods.: Formulations were prepared with propylene glycol (0.275%), carboxymethyl cellulose (CMC, 0.5% and 1.0%) of low and medium viscosity and hydroxypropylmethyl cellulose (0.3%). Quantification of 5-MCA-NAT (100 μM) was assessed by HPLC. In vitro tolerance was evaluated by the MTT method in human corneal-limbal epithelial cells and normal human conjunctival cells. In vivo tolerance was analyzed by biomicroscopy and specular microscopy in rabbit eyes. The ocular hypotensive effect was evaluated measuring IOP for 8 hours in rabbit eyes. Results.: All the formulations demonstrated good in vitro and in vivo tolerance. 5-MCA-NAT in CMC medium viscosity 0.5% was the most effective at reducing IOP (maximum IOP reduction, 30.27%), and its effect lasted approximately 7 hours. Conclusions.: The hypotensive effect of 5-MCA-NAT was increased by using bioadhesive polymers in formulations that are suitable for the ocular surface and also protective of the eye in long-term therapies. The use of 5-MCA-NAT combined with bioadhesive polymers is a good strategy in the treatment of ocular hypertension and glaucoma

New fish product ideas generated by European consumers

Food lifestyles are changing; people have less time to spend on food purchase and preparation, therefore leading to increasing demand for new food products. However, around 76% of new food products launched in the market fail within the first year (Nielsen, 2014). One of the most effective ways to enhance new products’ success in the market is by incorporating consumers’ opinions and needs during the New Product Development (NPD) process (Moon et al., 2018). This study aimed to explore the usefulness of a qualitative technique, focus groups, to generate new aquaculture fish product ideas as well as to identify the most relevant product dimensions affecting consumers’ potential acceptance.Peer ReviewedPostprint (published version

Effectiveness of universal multiple-risk lifestyle interventions in reducing depressive symptoms:Systematic review and meta-analysis

Though many studies have explored the association between single-risk lifestyle interventions and depression, unhealthy lifestyle factors often co-occur, with adults engaging in two or more risk behaviours. To date, little is known about the effectiveness of universal multiple-risk lifestyle interventions to reduce depressive symptoms. We conducted a SR/MA to assess the effectiveness of universal multiple-risk lifestyle interventions (by promoting a healthy diet, physical activity and/or smoking cessation) to reduce depressive symptoms in adults. We searched MEDLINE, Scopus, CENTRAL, PsycINFO, WOS, OpenGrey, the ICTRP and other sources from inception to 16 September 2019. We selected only randomized controlled trials, with no restrictions on language or setting. Our outcome was the reduction of depressive symptoms. We calculated the standardized mean difference using random-effect models. Sensitivity, sub-group and meta-regression analyses were performed. Of the 9386 abstracts reviewed, 311 were selected for full-text review. Of these, 23 RCTs met the inclusion criteria, including 7558 patients from four continents. Twenty RCTs provided valid data for inclusion in the meta-analysis. The pooled SMD was −0.184 (95% CI, −0.311 to −0.057; p = 0.005). We found no publication bias, but heterogeneity was substantial (I2 = 72%; 95% CI: 56% to 82%). The effectiveness disappeared when only studies with a low risk of bias were included. The quality of evidence according GRADE was low. Although a small preventive effect was found, the substantial heterogeneity and RCTs with lower risk of bias suggested no effectiveness of universal multiple-risk lifestyle interventions in reducing depressive symptoms in a varied adult population. Further evidence is required

Market validation, technical and socioeconomic analysis of fish products

Deliverable 5.5Deliverable 5.5 “Market validation, technical and socioeconomic analysis of fish products”, covers the results from several studies involving consumer activities performed in Task 5.4 “Market validation”; the profiling of key EU consumer segments for new product adoption (through large-scale quantitative and qualitative surveys), the identification of the optimal product configuration (through choice experiments), the identification of the optimal combination of packaging attributes (validated through neuroscience), the assessment of sustainability dimensions (choice experiment) and finally the validation tests (Home Use Tests and online questionnaires) of the new products in three European countries (Spain, France and Germany). It also includes the results of Task 5.5 “Technical and economic feasibility analysis of products” performing case studies for producing the four new food products (grilled seabass with lemon, sea and mountain burger, seabream breaded bites and organic seabream with couscous) developed in the framework of MedAID. The information provided could facilitate the implementation of these developments by industry.Postprint (published version